Fmoc-(S)-3-Amino-4-(3,4-difluoro-phenyl)-butyric acid

Fmoc-(S)-3-Amino-4-(3,4-difluoro-phenyl)-butyric acid - Names and Identifiers

Name	Fmoc-(S)-3-Amino-4-(3,4-difluoro-phenyl)-butyric acid
Synonyms	RARECHEM AK PT F037 FMOC-PHE(3,4-F 2)-(C*CH2)OH (S)-FMOC-3,4-DIFLUORO-BETA-HOMOPHE-OH FMOC-(S)-3-AMINO-4-(3,4-DIFLUOROPHENYL)BUTANOIC ACID Fmoc-(S)-3-Amino-4-(3,4-difluoro-phenyl)-butyric acid FMOC-(S)-3-AMINO-4-(3,4-DIFLUORO-PHENYL)-BUTYRIC ACID (S)-3-(FMOC-AMINO)-4-(3,4-DIFLUOROPHENYL)BUTYRIC ACID N-BETA-(9-FLUORENYLMETHOXYCARBONYL)-L-HOMO(3,4-DIFLUOROPHENYL)ALANINE N-(9-FLUORENYLMETHOXYCARBONYL)-(S)-3-AMINO-4-(3,4-DIFLUOROPHENYL)BUTANOIC ACID
CAS	270063-55-3

Fmoc-(S)-3-Amino-4-(3,4-difluoro-phenyl)-butyric acid - Physico-chemical Properties

Molecular Formula	C25H21F2NO4
Molar Mass	437.44
Density	1.332±0.06 g/cm3(Predicted)
Boling Point	635.8±55.0 °C(Predicted)
pKa	4.30±0.10(Predicted)
Storage Condition	Inert atmosphere,2-8°C

Fmoc-(S)-3-Amino-4-(3,4-difluoro-phenyl)-butyric acid - Risk and Safety

Safety Description	S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes.
WGK Germany	3
FLUKA BRAND F CODES	10
Hazard Class	IRRITANT

Fmoc-(S)-3-Amino-4-(3,4-difluoro-phenyl)-butyric acid - Introduction

Fmoc-(S)-3-Amino-4-(3,4-difluoro-phenyl)-butyric acid is an organic compound with the chemical formula C23H19F2NO4. It is an unnatural amino acid with a chiral center and therefore has two enantiomers:(S)-Fmoc-(S)-3-Amino-4-(3,4-difluoro-phenyl)-butyric acid and (R)-Fmoc-(S)-3-Amino-4-(3,4-difluoro-phenyl)-butyric acid.

Fmoc-(S)-3-Amino-4-(3,4-difluoro-phenyl)-butyric acid is often used as a reagent to protect amino acid residues in chemical synthesis, can be used for peptide synthesis in solid phase synthesis (SPPS), and is an important intermediate for the synthesis of peptides and proteins with specific sequences. It is also commonly used in the fields of drug discovery, protein engineering and organic synthesis.

The method for synthesizing Fmoc-(S)-3-Amino-4-(3,4-difluoro-phenyl)-butyric acid is generally to introduce an Fmoc protecting group into an amino acid molecule by reaction. Specific synthetic methods can refer to the relevant literature or chemical handbook.

Regarding safety information, Fmoc-(S)-3-Amino-4-(3,4-difluoro-phenyl)-butyric acid is generally relatively safe under normal operation. However, as a chemical reagent, it should strictly follow the laboratory's safety procedures and wear appropriate protective equipment, such as gloves and goggles. At the same time, according to personal health status and use environment, risk assessment and safety protection measures should be carried out.

Last Update：2024-04-09 21:11:58